Molecular biology bioinformatics and comparative genomics
Researchers in ithree institute have used molecular biological methods to discover and produce vaccines for various animal and human diseases (neosporosis, fasciolosis and coccidiocis). In recent times, the enormous and rapidly growing genomic information in the public databases has dramatically altered how we study infectious diseases.
Bioinformatics is the use of mathematical and data mining tools to identify and understand the biological function of families of genes and proteins. Bioinformatics also provides tools for interrogating and interpreting this information to discover fundamental processes in bacterial and parasite biology, not only at the molecule level but also at the whole organism and community level.
Combined with the nexus of ithree institute researchers we employ bioinformatics in the discovery of molecules important for infectious disease (and hence vaccine and drug targets), elucidate networks and processes involved in cell division, cell growth and drug resistance and investigate the genomes of newly discovered infectious gut flora.